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10.1016/0003-9861(57)90478-2 49 BerjotM.MarxJ.AlixA

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Circulating MOTS-c declines with age and tracks with insulin resistance, making it both a potential longevity biomarker and a therapeutic target

To confirm that the PAT activity was responsible for the mislocalization of substrates in the SwissKASH assay, we generated zDHHC-inactive constructs by a Cys-to-Ser mutation in the catalytic DHHC domain 36

Before mutagenesis, the D39 strain had a previous passage in mice, as described [19]