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In summary, genetic risk factors for development of serious DILI at relatively low levels of APAP overdose seem likely to exist but the limited studies performed to date need to be followed up by genome-wide approaches using larger numbers of confirmed DILI cases or possibly further studies on volunteers showing transient ALT elevation

Additionally, green-synthesized nanoparticles stand out as eco-friendly and cost-effective alternatives for versatile applications [218]

10.1093/ijnp/pyx094 55

However, a current limitation of microfluidic approaches is scalability: producing large batches of nanocarriers via microfluidics is challenging due to the low throughput of individual microchannels and issues like microchannel clogging (85)

Dayer, R., Fischer, B