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This compound crosses the BBB and does not need to be manufactured by recombinant methods at high cost compared to HGF, which represents an obvious advantage

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Similar results were reported in a recent study (Ashraf et al., 2016)

Histology results Before the initiation of therapy, at 10 min after injury induction, a large hemorrhagic zone was present over the lateral and posterior white columns in all of the rats, but there were no changes in the gray matter

Throughout this period, the favorable safety profile remained consistent with no delayed-onset adverse effects or concerning laboratory changes emerging over time