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these functions are mediated by the mitochondrial protein translocation-associated degradation (mitoTAD) pathway, mitochondrial-associated degradation (MAD) system, mitochondrial ubiquitinproteasome system (UPS), mitochondrial unfolded protein response (UPR mt ), and mitochondrial-derived vesicle carriers (MDVs)

In this regard, studies on PEG-IGF-I have shown little side effect and no loss of long-term beneficial activity

How to Cite The Nigerian Health Journal , 25 (4), 1565-1572

Several viral infections, and the progression of virus-induced diseases, especially those associated with COVID-19, are characterized by an alteration in the intracellular redox balance ( FIGURE 8 Atherosclerosis, a chronic inflammatory disease, may be an ideal environment for the high viral replication capabilities of SARS-CoV-2 in human cells, enhancing hyper-inflammation secondary to immune system dysregulation (Figure 9) that leads to adverse outcomes, as shown in patients with cardiovascular risk factors (258, 259)

l-glutathione is a tripeptide comprises of three amino acids: l-glutamate, l-cysteine and glycine