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Studies have revealed that the GH/IGF-1 axis plays a key role in the aging process of humans and animals ( GH receptor is a member of the class I cytokine receptor family and exists in almost all cell types in the human body (Waters et al., 1999)

It further indicates a primary contributor to the elevated morbidity and mortality observed in individuals with diabetes

Necroptosis is usually triggered via Toll-like receptors or death receptors that include TNF receptor-1 (TNFR1) 49 acting via RIPK1 to sequentially activate RIPK3 and MLKL

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Further investigation into their mechanisms of action is essential, as this research holds considerable importance for preventing and treating OSAHS in postmenopausal women