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Moreover, none of the included studies conducted systematic analyses of small moleculeprotein interactions, and the pharmacokinetic relevance of the doses used in vitro versus in vivo studies remains largely unaddressed

Because many metabolic reactions rely on enzymes, maintaining adequate zinc levels helps ensure these systems operate efficiently

of Small Business Programs, Report for Fiscal Year 2009 , May 2011, p

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Hadzhieva M, Kirches E, Wilisch-Neumann A, Pachow D, Wallesch M, Schoenfeld P et al (2013) Dysregulation of iron protein expression in the G93A model of amyotrophic lateral sclerosis