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Methods Animals Animal experiments were performed with adherence to all national and local guidelines and regulations, the Guide for the Care and Use of Laboratory Animals 25 , and the ARRIVE guidelines, and with the approval of the Institutional Animal Care and Use Committee at The University of Texas Medical Branch (UTMB)

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The effects of human GH and its lipolytic fragment (AOD9604) on lipid metabolism

Typical daily range: 2.55 mg per day 2.5 mg/day to start, increasing to 5 mg/day, or split as 2.5 mg twice daily

Originally developed as an anti-obesity drug, AOD-9604 is a synthetic fragment derived from human growth hormone (hGH), specifically the 177-191 amino acid sequence