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Four molecule families have peer-reviewed clinical evidence supporting their use in microinfusion-style delivery: copper tripeptide GHK-Cu (collagen synthesis, gene-expression modulation), recombinant epidermal growth factor or sh-Oligopeptide-1 (keratinocyte proliferation, dermal restructuring), polydeoxyribonucleotide PDRN (adenosine A2A receptor activation, fibroblast stimulation, anti-melanogenesis), and a multi-molecular-weight hyaluronic acid system (50 kDa to 2000 kDa fractions, each with different penetration depth and biological role)

doi: 10.1046/j.1469-7580.2003.00195.x

It was observed to possibly decrease fragmentation in post-ovulatory aged oocytes and during parthenogenetic activation a process where an egg develops into an embryo without fertilization

Store GHK-Cu after reconstitution in conditions that prevent this outcome: refrigerated, sealed, and protected from light

The subcutaneous layer is thicker, making it nearly impossible to accidentally inject into muscle