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IF has been shown to enhance the gene expression of certain M2 macrophage markers, partly through increasing adiponectin levels [95, 99]

Peptide-based liquid droplets as emerging delivery vehicles

Gpx4 uses GSH as cofactor and is needed to prevent lipid peroxidation, which depends on ROS

Is involved in several other cellular events, such as synthesis of proteins and DNA, transport, enzyme activity, nutrient metabolism, cell protection and protein S-glutathionylation

Table 1 shows the pharmacological properties and practical advantages of these agents relative to Erastin, providing a reference framework for selecting candidates and delivery strategies in preclinical models of EMS