Pharmacol Ther (2011) 34:108897
The standard recommendation is to initiate treatment with a 20 mg dose administered twice daily, with a maximum approved dosage of 80 mg twice daily
* Fruiting bodies of gourmet wild and cultivated mushrooms, including Hen of the Woods, Shiitake, King Boletes, Enokitake, and Oyster Mushroom species, contained ergothioneine levels 50x to 1000x higher than the common cultivated button mushrooms
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The patient should not be a chain smoker , heavy smoker, addicted or alcoholic