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And it influences the hypothalamic-pituitary-adrenal axis, which connects immune regulation to stress response, an important consideration given that psychological stress is a known trigger for lupus flares

Xu F, Yu S, Qin M, Mao Y, Jin L, Che N, et al

Therefore, further studies are required in this regrade

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To confirm that DBS stimulation site targeted appropriate locations, we examined the spatial overlapping, measured by Dice coefficient, between the VTA overlap across patients and the STN sweet spot from the DBS-SS dataset 39