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Fatigue is common and can be caused by many things, including: Iron deficiency Low vitamin D Thyroid issues Poor sleep quality or sleep apnoea Stress and burnout Low mood/anxiety Dietary patterns and hydration Long-term conditions Thats why we always recommend basing B12 treatment on clinical context, and ideally blood test results, rather than guessing

Individuals who maintain a healthy lifestyle and consume a well-balanced diet may experience longer-lasting benefits from B12 injections

Nature Lee E, Walker C, Ayadi B

Previous studies showed MDA, SOD and GSH-PX played vital roles in ROS-mediated lipid peroxidation and liver injury [2224]

In pathophysiological conditions, PKD-mediated phosphorylation of Ser637 has been demonstrated to enhance mitochondrial fragmentation (Jhun et al., 2018)