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For treating a deficiency, injections are usually given frequently at the start, for example, several times per week or every other day for a couple of weeks, to quickly build up body stores

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For the ultra-low protocol using a 30 mg vial at 2.5 mg/mL (12 mL total), the math shifts

Every vitamin B12 shot at our La Grange clinic is given as an intramuscular injection into the deltoid (upper arm) by a licensed clinician under nurse-practitioner supervision

Reported side effects in human anecdotal use are generally mild and may include: Mild nausea, particularly with oral administration Redness, itching, or irritation at the injection site Temporary dizziness or mild headache Changes in appetite or weight A significant theoretical concern revolves around its pro-angiogenic properties