The science is biologically plausible, the early findings are encouraging, and the available safety data appears favorable, but its important to be transparent about what we know, what we dont know, and where the evidence still needs to mature
This work was supported by the National Institutes of Health (5R01HL148151)
The milky white veins are a helpful sign, suggestive of its benefits
Beyond lipid enzymes and microRNAs, exosomes derived from ferroptotic neurons also carry immunogenic DAMPs, which can be internalized by both microglia and astrocytes, triggering their innate immune recognition systems and initiating secondary immune responses
Inflammatory cytokine regulation of transgene expression in human fibroblast-like synoviocytes infected with adeno-associated virus