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Its toxic effects extend to male reproductive health, where it adversely effects on testicular function, impairs spermatogenesis, and induces oxidative stress through mechanisms such as elevating the Reactive oxygen species concentration, mitochondrial dysfunction, and cellular apoptosis which severely affects the reproductive health (74, 75)
In conclusion, the pathological features and pathogenic factors of PD include the excessive accumulation of -Syn in the substantia nigra pars compacta or its gene mutation
There are no toxicity levels
Hodgson (Eds.) The Athletic Horse: Principles and Practice of Equine Sports Medicine
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