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The researchers observed a significant increase in glutathione (GSH) synthesis (approximately 85 percent) and a 64 percent rise in total GSH levels in red blood cells

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In oral supplementation trials (250-1000 mg/day for up to 6 months), side effects were mild and transient, including occasional gastrointestinal symptoms

Extracts of rabbit reticulocytes (obtained by injecting rabbits with a chemicalphenylhydrazinethat causes a severe hemolytic anemia, so that the red cells are almost completely replaced by reticulocytes) are widely used as an in vitro system for synthesizing proteins