Dioscorea septemloba: network pharmacology analysis suggests that its active components may regulate inflammation and urate metabolism through multiple targets ( 3.2.4 Exploratory non-pharmacological approaches Emerging non-pharmacological strategies are under investigation
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Toxicology 149:4350 Thomas C, Mackey MM, Diaz AA, Cox DP (2009) Hydroxyl radical is produced via the Fenton reaction in submitochondrial particles under oxidative stress: implications for diseases associated with iron accumulation
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2.2.3 Cholesterol metabolism in HCC Given the low expression of low-density lipoprotein receptor (LDLR), the transmembrane receptor for cholesterol, facilitates upregulated cholesterol synthesis, the expression of LDLR seems to be notably lower than that in normal cells surrounding the tumor in HCC (Chen et al., 2021)
