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Synapses are critical structures for information transmission between neurons, and synaptic dysfunction can lead to neurological behavioral changes, such as deficits in learning and emotional disturbances

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Notably, BAY-876SU056 combination treatment in this regimen seemed to be well tolerated in WT mice, as body weight change and histology of pathologically examined organs (liver, lung and kidney) were indistinguishable between vehicle and combination treatment cohorts (Extended Data Fig

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