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Pipecolic acid 0 ImagesPipecolic acid is an orally bioavailable, blood-brain barrier-permeable metabolite of lysine with antioxidant , inhibitor, and inducer activity

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Its primary mechanism is the upregulation of telomerase, the enzyme responsible for maintaining and extending telomeres, the protective end-caps on DNA strands

et al., 2021) demonstrated that the administration of metformin changed the relative abundances of metabolites such as carbohydrates, amino acids, and fatty acids as well as specific gut bacteria ( Escherichia, Romboutsia, Intestinibacter, and Clostridium )