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Previous studies have demonstrated that AR signaling (DHT, 5-alpha-dihydrotestosterone) primarily enhances glutamine (Gln) uptake by regulating the expression of various Gln transporters, such as SLC1A4 (ASCT1), SLC1A5 (ASCT2), SLC3A2 (4F2hc), SLC7A5 (LAT1), and SLC43A1 (LAT3), to meet the proliferative and differentiative demands of PCa cells (39, 233, 236)
Some practitioners cite glutathione's general antioxidant benefits and theoretical mitigation of metabolic stress
Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4
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