The tissue-specific effect of l-carnitine was found in many experiments in mammals or fish, in which the carnitine content of muscle was relatively stable, whereas the liver was more sensitive to carnitine supplementation or deficiency ( Reference Li, Li and Qin 32 , Reference Morand, Bouitbir and Felser 48 , Reference Wchter, Vogt and Kreis 49 )
Direct lysosome-based autophagy of lipid droplets in hepatocytes
Many factors, including oxidative stress and intermediate oligomer conformation, play important roles in the pathogenesis of Parkinsons disease in different metabolic pathways
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Additionally, upregulation of SLC6A14 expression has been observed in gastric cancer, and depletion of SLC6A14 leads to the suppression of epithelial-mesenchymal transition-induced metastasis in gastric cancer through disruption of the PI3K/Akt/mTORC1 pathway [60]