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Compared with the Con group, DSS-treated mice showed reduced T cell mean fluorescence intensity, accompanied by increased IFN- + T and IL-17 + T mean fluorescence intensity, indicating T-cell-mediated pro-inflammatory activation in UC

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Gain-of-function mutation in ACOX1, Mitchell Syndrome: Gain-of-function mutation in peroxisomal acyl-CoA oxidase 1 (ACOX1) is a very rare heterozygous missense variant (p

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