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Individuals with heavy metal exposure may also benefit from ALA IV therapy, since ALA can cross the blood-brain barrier and help draw certain metals, such as mercury , away from tissues

FIGURE 2 Glutamate Excitotoxicity Cascade in PD The excitotoxic cascade is triggered by excess extracellular glutamate, which may eventually lead to cell injury and death (Siesj et al., 1989)

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In retina facing high oxidative burden from light exposure and metabolism, enhanced antioxidant defenses critical for long-term photoreceptor and RPE survival

The evidence base for any cycling protocol is essentially absent