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[DOI] [PubMed] [Google Scholar] 145.Lckel C., Picard F., Raifer H., Campos Carrascosa L., Guralnik A., Zhang Y., Klein M., Bittner S., Steffen F., Moos S., et al

additionally, more research is required to investigate differences between NAD + modulators within different tissues, different models or pathologies, administration or exercise regimens, and how to successfully translate these findings to humans, while several clinical trials have already been conducted

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Research indicates that low-dose etoposide (2 M) can induce senescence in HepG2 liver cancer cells, while higher doses (100 M) lead to apoptosis [62]