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the receiving medium placed in the diffusion cells must be one which mimics the physiological condition of the skin

Although these mechanisms suffer from the problem that there are few relevant studies and insufficient evidence, we can still believe that these potential mechanisms are worth validating and exploring, and that they may hold the secret to sustained antidepressant effect

Preservative solution is recommended, but if the product will be used relatively quickly and kept refrigerated, deionized water or a blend of both may be used.

Mokdad AH, Ballestros K, Echko M, Glenn S, Olsen HE, Mullany E

& Desimone, R