The immobilization enzymes were washed three times with 2 mL of 20 mM potassium phosphate buffer (pH 8.0)
Inhibition of GLS, using agents such as BPTES or siRNA, effectively reduces viability across all PCa cell lines, with AR-independent cells showing heightened sensitivity (35)
Beyond detoxification, glutathione serves critical functions in maintaining cellular redox balance, regulating inflammatory responses, supporting mitochondrial function and energy production, protecting against DNA mutations, and maintaining immune cell function
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