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2) The study conducted by the research team of Li et al meticulously delineated the role of FOXO4 in Leydig cell senescence and its impact on male fertility, while also demonstrating the therapeutic efficacy of FOXO4-DRI in alleviating age-related testosterone and spermatogenesis insufficiencies

While antiangiogenic therapies hold promise, their use must be carefully tailored to specific pathological contexts to avoid disrupting compensatory mechanisms that support neuronal health