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When the production of ROS exceeds the counteracting mechanisms of the antioxidant system, oxidative stress will occur, resulting in oxidative damage to proteins, nucleic acids and lipids, affecting the normal functioning of the body and inducing the occurrence of various diseases such as NDs 22 , 24

Due to their unique characteristics- such as wide size range, adjustable shape, and ease of modification, it is gaining more attention in the medical field, particularly for disease diagnosis and treatment[166], [167], [168], [169], [170]

Positive charge patterning and hydrophobicity of membrane-active antimicrobial peptides as determinants of activity, toxicity, and pharmacokinetic stability

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