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These peptides primarily act through the GH/IGF-1 axis, which activates the PI3K/Akt/mTOR cascadestimulating satellite cell proliferation, muscle protein synthesis, and chondrocyte matrix production
Sikiric et al., 2017
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Tam emphasized that "unfortunately, there just isn't enough valuable, statistically significant evidence that points us to be able to recommend them safely." Newer injectable peptides are not FDA approved "Insulin and GLP-1s are designed for specific disease, so we know who's a good candidate for them," Dr
Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers
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