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For individuals with conditions like pernicious anaemia, an autoimmune disorder that attacks the protein needed to absorb B12, oral supplements are often completely ineffective

doi: 10.1016/j.freeradbiomed.2018.12.013 82 GreenYSFerreiraDSMFujaDGReichertECCamposARCowmanSJet al

coli Keio Knockout Collection 21 were gifts from Drs

The RRP consists of a small fraction of total vesicles that are physically docked at the active zone, molecularly primed by active zone proteins (such as RIM and Munc13) into a SNARE-assembled, fusion-competent state (Kaeser and Regehr, 2017)

AD is the recipient of an Alzheimer Nederland grant (WE.03- 2018-04, the Netherlands), and a Rosalind Franklin Fellowship co-funded by the European Union and the University of Groningen