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This is true of virtually every longevity intervention currently in use, including metformin

Also, don't take astaxanthin if you're allergic or sensitive to: Similar carotenoids, such as canthaxanthin A source of astaxanthin, such as the algae that produce it Medicines that inhibit 5-alpha-reductase, such as dutasteride (Avodart, Jalyn) or finasteride (Propecia, Proscar) Avoid the supplement if you're pregnant or might become pregnant

Nrf2 activators like sulforaphane have a potential role with dual antiviral and anti-inflammatory properties in the management of viral pneumonia, a serious complication in COVID-19 disease (Bousquet et al., 2020

Neurologic conditions like multiple sclerosis or Parkinsons

Bevacizumab and paclitaxelcarboplatin chemotherapy and secondary cytoreduction in recurrent, platinum-sensitive ovarian cancer (NRG Oncology/Gynecologic Oncology Group study GOG-0213): a multicentre, open-label, randomised, phase 3 trial