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Investigations of the effects of acute normovolemic anemia induced by blood loss ( i.e ., without concomitant hemolysis) on cardiovascular hemodynamics were started almost 50 years ago by Fowler et al

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PS-MPs interfere with the balance of the antioxidant system via the Nrf2-Keap1-HO-1/NQO1 axis, leading to altered antioxidant enzyme activity, increased lipid peroxidation, and induction of autophagy-dependent ferroptosis in cerebellar tissue