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The body can only absorb approximately 1.5 g per dose through the intrinsic factor mechanism, which is why higher doses rely on passive diffusion for additional absorption

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10.1038/s41380-020-0793-6 70 MairD.ParisA.ZaloumS

Protein expression is regulated at multiple levels, including post-transcriptional and post-translational levels [32,33,34,35]