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An increase in the percent of recognition index in the treatment group of edaravone (only 10 mg/kg) (53 6%), TPPU (52 4%) and sEHI + DHA (63 5%) were observed in comparison to diabetic control rats

Results were plotted as boxplots showing mean, 5th and 95th percentile of the dataset

People using insulin or sulfonylureas may need dose adjustments to reduce hypoglycemia risk

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Harding to test whether a stable, brain-penetrant AngIV analogue could recapitulate AngIVs reported cognitive effects in mammalian models