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doi: 10.1038/s42255-019-0041-z 74 SharmaAMahMRitchieRHDe BlasioMJ

Abnormal copper accumulation in the striatum of HC patients has been linked to the copper binding facilitated formation of amyloid- copper transporter Ctr1, rlike bodies of the huntingtin (Htt) protein [284, 285]

This growing focus is attributable to its broad-spectrum biological activities, including anti-inflammatory, antioxidative, immunomodulatory, neuroprotective, antiproliferative, antibacterial, and anticancer effects (34)

The HMONs-MnPpIX-PEG system was quickly broken down by GSH, which enhanced the therapeutic efficiency of sonodynamic treatment