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In patients with progressive myoclonus epilepsy, a GSTT1 -null genotype has been associated with increased risk of developing the disease where it might contribute to enhanced susceptibility to oxidative stress 60

Therefore, the relationship between tinnitus and these drugs is complex, and they may help improve symptoms in some people

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Another published review of the available studies of the drug concluded that the evidence does not support the use of piracetam in the treatment of people with dementia or cognitive impairment, but suggested that further investigation might be warranted