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Furthermore, interaction with activated microglia can induce astrocytes to adopt a neurotoxic phenotype, impairing their essential support functions for neurons and exacerbating neuroinflammation [33]

Disruption of Brain Redox Homeostasis, Microglia Activation and Neuronal Damage Induced by Intracerebroventricular Administration of S-Adenosylmethionine to Developing Rats

Ginger rhizome also showed hypotensive effects in rats, possibly through negative inotropic and chronotropic effects and endothelium-independent vasodilation by blocking VDCCs (563, 569)

Therefore, caution is warranted when extrapolating conclusions from one model to another

B12 is critical for cell division and organ formation, especially during the rapid cell growth of the first trimester [*]