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Tacrolimus is extensively distributed in the whole body but its distribution in solid organ tissue behaves similarly to lymphocytes and is dependent on P-gp expression and intracellular metabolism

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This protocol focuses on cellular signaling and metabolic regulation pathways that help maintain healthy glucose metabolism, calorie utilization, and body composition

Membrane-bound metallothionein 1 of murine dendritic cells promotes the expansion of regulatory T cells in vitro