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21 , 22 This process requires the presence of H 2 O 2 as an oxidizing agent catalyzed by thyroid peroxidase (TPO) in the thyroid and by lactoperoxidases (LPO) in the breast (Figure 1)

In a further therapeutic study, folate was found to serve as a supplement to restore the SAM/SAH ratio to benefit patients

Theres not enough evidence to show the possible negative effects of taking high doses of vitamin B12.

4.1.1 Enzymatic systems Superoxide dismutases are the first line of defense, dismutating superoxide (O 2 ) into H 2 O 2 and O 2