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These feelings of pleasure and relief brought on by nicotine could possibly be an explanation as to why many depressed people start using nicotine in the first place

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Mainstream smoke chemistry and in vitro and in vivotoxicity of the reference cigarettes 3R4F and 2R4F

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In contrast, our study employed a larger sample size, utilized serum cotinine levels as the independent variable, examined a more comprehensive range of tobacco products, and implemented rigorous control measures for confounding variables