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Studies have suggested that low doses have a depressant effect, whilst higher doses have stimulant effect." The health risks of smoking are not uniform across all smokers but vary according to amount of cigarettes smoked, with those who smoke more cigarettes at greater risk, although light smoking is still a health risk

However, those results only held true for the surface of the throat the bacteria that cause gonorrhea were more likely to persist deeper into the throat

Multiscale cancer modeling

Dentists use high-concentration bleaching agents that penetrate deep into the enamel, breaking down those stubborn stains

Ronald Reagan hawked Chesterfields .