Figure 1 Materials and methods A search of scientific literature was conducted using the PubMed database ( The following Medical Subject Headings (MeSH) terms were used: e-cigarettes AND flavor AND nicotine AND e-liquid AND cytotoxicity AND cellular damage and health AND adolescent AND young people. We included publications from 2020 to 2025 because fourth-generation electronic cigarettes appeared on the market in 2020 ( in vitro studies, in silico models, and studies using cannabis cigarettes or tobacco flavors, hookahs, nicotine pouches, and waterpipes
It was said that he referred to his secretaries as Little Miss Nitwits and that the word failure was missing from his vocabulary (despite numerous setbacks)
In addition to its harmful constituents, cannabis contains cannabinoids, such as cannabidiol (CBD) and THC, which have demonstrated anti-inflammatory, bronchodilatory, and even antineoplastic properties in preclinical models (14,15)
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