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They let me sit on it, and hand me the wooden goblet used by their volunteers

Overcoming Tobacco Machinery Obsolescence Machinery obsolescence is a significant challenge, especially in an industry with a long history like tobacco production

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What made the difference

In KS, a mutation in the FERMT1 gene results in loss of function, leading to keratinocyte detachment, duplication of the lamina densa, and multiple cleavage planes at different levels of the dermoepidermal junction, beginning at birth.5,7 From the first years of life all 4 patients presented skin fragility that subsequently diminished, leaving patients with cutaneous atrophy and poikiloderma predominantly in photo-exposed areas