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In the second stage, we used structural equation modeling (SEM) to estimate the parameters of the hypothesized mediation model of the effect of a ffect on tobacco product use (cigarettes / e-cigarettes) via perceived risk of the product, while adjusting for covariates (gender, age, race/ethnicity, and education)

The researchers primary outcome measures were abstinence from smoking after at least six months, adverse events, and serious adverse events

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