The placebo group claimed a remarkable 0% placebo affect, very unusual
(JCEM 2006) conducted two randomized, double-blind, placebo-controlled trials in 57 healthy adults (ages 2161)

Abbreviations RA: Rheumatoid arthritis TCM: Traditional Chinese medicine BR: Bilirubin RM: Red blood cell membranes Cel: Celastrol ROS: Reactive oxygen species RES: Reticuloendothelial system HA: Hyaluronic acid PBS: Phosphate Buffered Saline MD: Molecular dynamics RMSD: Root mean square deviation SASA: Solvent-accessible surface area 1 H-NMR: Hydrogen nuclear magnetic resonance spectroscopy DMSO-d6: Dimethyl sulfoxide-d6 D 2 O: Deuterium oxide Cou6: Coumarin 6 DIR: 1,1-Dioctadecyl-3,3,3,3-tetramethylindotricarbocyanine iodine DCFH-DA: 2,7-dichlorofluorescein diacetate DAF-FM DA: 4-amino-5-methylamino-2,7-difluorofluorescein diacetate NO: Nitric oxide WB: Western blotting PCA: Principal component analysis DEGs: Differentially expressed genes KEGG: Kyoto Encyclopedia of Genes and Genomes micro-CT: Micro-computed tomography H&E: Hematoxylin and eosin SO-FG: Senna O-Fixed Green TRAP staining: Tartaric acid staining PBS: Phosphate-buffered saline ALP staining: Alkaline phosphatase staining ALT: Aminotransferase AST: Aspartate aminotransferase CCK8: Cell Counting Kit-8 UV-vis: Ultraviolet-Visible Spectrophotometryp FT-IR: Fourier Transform Infrared Spectroscopy LPS: Lipopolysaccharide SDS-PAGE: Sodium dodecyl sulfate-polyacrylamide gel electrophoresis References Smolen JS, Aletaha D, Barton A, Burmester GR, Emery P, Firestein GS, et al

However, lemons can also cause skin sensitivity due to its limonene content
Though the process was simple, I did find these steps a bit lumbering