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Key considerations : Prefer fast-acting forms such as nicotine gum or lozenges Use the lowest effective dose to control withdrawal symptoms Remove nicotine patches overnight if patches are used Document riskbenefit discussions with the patient It is important to note that using NRT for nicotine products other than cigarettes may be considered off-label, depending on jurisdiction and clinical guidelines

Epithelial Cell Mitochondrial Dysfunction and PINK1 Are Induced by Transforming Growth Factor-Beta1 in Pulmonary Fibrosis