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Specifically, the BAPC model assumes prior distribution of the age effect as follows: Considering that we are interested in the incident case counts for age group , with a period into the future, the following equation can be applied: In this study, we add an independent random effect to adjust for overdispersion

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After activation of the Wnt/-catenin pathway, -catenin is translocated to the nucleus and interacts with the transcription factor LEF/TCF to activate transcription

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