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Epigenetic alterations in arsenic-induced nephrotoxi- city Arsenic alters gene expression through epigenetic mechanisms, including DNA methylation, histone modification, and RNA methylation

Part A 109 (9), 15751587

doi: 10.3389/fphar.2021.698905 291 WangS.ShengY.TuJ.ZhangL

Consequently, the incidence of tobacco-associated cancers has been declining, and a recent report projects that the number of annual lung cancer deaths will drop by 63 percent within the next 50 years if the smoking rate continues to decrease in the future (48)(59)