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showed that the extract from electronic cigarettes (containing different flavours and nicotine quantity) applied to cultured myocardial cells at different dilution, both with or without nicotine, was cytotoxic at different concentrations irrespective of nicotine presence

states since have required that all cigarettes sold by 2012 must be fire safe, that is, have sharply reduced ignition strength or ability to start fires

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Innovations such as capsule filters in Rothmans or flavored slims in Capri provide customizable experiences, appealing to younger smokers (20-35 years)

For example, one small 2012 study found conflicting evidence on quitting smoking and testosterone