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Why is it that some people can smoke three packs a day and not get lung cancer, while others smoke far less and do get cancer

As smoke is continuously generated, new particles are introduced faster than many systems can remove them

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Methamphetamine causes addiction the fastest because it floods the brain with dopamine, producing immediate, intense euphoria

Then, using Monocle v2.8 26 , we carried out dimensionality reduction on the integrated expression using the DDRTree algorithm, and then ordered cells along a trajectory of pseudotime (using Monocles orderCells function